Biotech
Immune cells that are designed to soothe could improve treatment for organ transplants, type 1 diabetes and other autoimmune conditions. When the immune system overreacts and starts attacking the body, the only option may be to shut the entire system down and risk developing infections or cancer. But now, scientists may have found a more [...]
A new study has generated the largest-ever collection of exome data, which include genes that code for proteins — key to understanding health and disease. The study analysed DNA from over 100,000 participants from diverse backgrounds, providing important insights into certain genetic predispositions to support personalised and proactive medical guidance. The study focused on pathogenic [...]
Researchers have developed a novel bioprinting technique that uses spheroids, which are clusters of cells, to create complex tissue. This new technique improves the precision and scalability of tissue fabrication, producing tissue 10-times faster than existing methods. The technique further opens the door to developing functional tissues and organs and progress in the field of [...]
Researchers have made a significant advance in the field of molecular robotics by developing custom-designed and programmable nanostructures using DNA origami. This innovative approach has potential across a range of applications, from targeted drug delivery systems to responsive materials and energy-efficient optical signal processing. The method uses ‘DNA origami’, so-called as it uses the natural [...]
Researchers have made a significant step towards realising a form of ‘biological electricity’ that could be used in a variety of bioengineering and biomedical applications, including communication with living human cells. Iontronic devices are one of the most rapidly-growing and exciting areas in biochemical engineering. Instead of using electricity, these mimic the human brain by [...]
A newly developed nanomaterial - halide perovskite nanocrystals (HPNCs) - show potential as antimicrobial agents that are stable, effective and easy to produce. The material has been found to be effective at killing bacteria in a biofluid under visible light without experiencing light- and moisture-driven degradation common in HPNCs. A new method using two layers [...]
Engineers have developed a new way to improve mRNA delivery, developing an optimal “recipe” for ionizable lipids — key ingredients in lipid nanoparticles (LNPs), the molecules behind the Covid-19 vaccines and other innovative therapies. The method, described in Nature Biomedical Engineering, mirrors the iterative process of developing a culinary dish and may lead to safer, [...]
Cure51 has announced the UK launch of the Rosalind study, a groundbreaking initiative already underway in other parts of Europe that aims to unlock the secrets of exceptional cancer survivors. The UK phase, to be conducted in collaboration with Cambridge University Hospitals and seven other top UK-based institutions, has been approved the NHS Health Research [...]
Researchers holding 3D printed PA-blood constructs. Credit: University of Nottingham Scientists have created a new ‘biocooperative’ material based on blood, which has shown to successfully repair bones, paving the way for personalised regenerative blood products that could be used as effective therapies to treat injury and disease. Researchers from the Schools of Pharmacy and Chemical [...]
Researchers are working to potentially reduce the growing rate of antibiotic-resistant infections in open bone fractures by employing nanotechnology to bolster a centuries-old treatment. More than 150,000 people in the United States suffer open bone fractures every year. About 10% of them will develop an infection which can lead to reduced limb function, secondary operations, [...]
