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Digital twin health innovation backed by investors

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Precision health firm Twin Health has raised US$140m (£103m) in series C funding as it scales its service in the US and globally.

Twin Health, founded in 2018, is the creator of the Whole Body Digital Twin system, designed to help reverse and prevent chronic metabolic diseases.

Powered by artificial intelligence, it provides a dynamic representation of an individual’s unique metabolism, built from thousands of data points collected daily via non-invasive wearable sensors and self-reported preferences.

The Whole Body Digital Twin is a predictive model that provides individualised nutrition, sleep, activity and breathing guidance to patients and their healthcare providers, helping to reverse and prevent multiple chronic metabolic diseases.

Jahangir Mohammed, founder and CEO of Twin Health, said: “We are each gifted a body. If given a chance, it can heal itself. Our Whole Body Digital Twin lives alongside you – giving you a view into your beautifully complex biology, continuously learning about your metabolism and telling you what you can do to improve your health in the moment.”

Chronic metabolic disease is widespread and growing. The global prevalence of Metabolic Syndrome is estimated as 20-25 per cent.

Worldwide, 415 million people are living with diabetes, and more than 500 million will have diabetes by 2040, according to the CDC.

Chronic metabolic diseases, such as type 2 diabetes, can start as an individual’s metabolism breaks down over time.

Medical research has demonstrated that each person’s metabolism functions uniquely, presenting significant challenges to healthcare providers’ understanding and ability to customize treatment for every single person.

Twin Health’s service consists of multiple sensors including continuous glucose monitors and fitness watches, comprehensive blood tests and the development of each member’s individualised Whole Body Digital Twin; as well as consultations with healthcare providers and Twin coaches.

The technology continuously monitors the health of the individual and enables healthcare providers and Twin coaches to take quick actions.

Through an easy-to-use app, patients and their care team are provided individualised, precise, timely guidance across nutrition, sleep, activity and breathing.

Healthcare providers can access organised biomarker data and medication reduction recommendations for their patients, with the goal of reversing chronic disease.

Twin Health’s clinical research team is conducting the world’s first randomised controlled trial (RCT) for reversing chronic metabolic disease using digital twin technology.

Early RCT data were recently presented and published in the American Diabetes Association’s Diabetes journal, with first of its kind health outcomes. Patients had an average

Dr Toby Cosgrove, executive advisor/Cleveland Clinic, who is on Twin Health’s board of directors, said: “The Whole Body Digital Twin is delivering a new standard of care, empowering physicians and patients to make highly personalised data-driven decisions based on real-time feedback coming from patients’ own bodies,”

Used as early as the 1960s, digital twin technology is at a new inflection point, applied across sectors ranging from auto to aircraft and energy thanks to advances in sensor technology, connectivity, and the computing power required to machine learn with massive volumes of data.

Through application of this advanced technology to one of the most complex systems of all – the human metabolism – Twin Health is addressing the root cause of chronic metabolic disease.

Company founder Jahangir Mohammed is a serial inventor, entrepreneur and tech pioneer with early successes in mobile connectivity, the Internet of Things and digital twin technology.

He founded Kineto Wireless in 2000, pioneering the use of WiFi technologies in mobile phones for indoor voice and data. He later founded and built Jasper Technologies into a leading global IoT platform, acquired by Cisco for US$1.4bn in 2016.

“The Whole Body Digital Twin became my life’s work after my eyes were opened to the magnitude of chronic disease globally,” he said.

“I had seen too many loved ones impacted by the daily challenges of living with these diseases, forever changing the futures they imagined.

“The impact the Twin service has had on our members’ lives energizes and inspires me, hearing their stories as they begin to understand the intricacies of their own metabolism and feel empowered to heal from the inside out.”

The Series C funding round includes ICONIQ Growth, Sequoia Capital India, Perceptive Advisors, Corner Ventures, LTS Investments, Helena and Sofina, enabling Twin Health to scale its Whole Body Digital Twin service.

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