Biotech
A UK company that has developed a novel gene-editing tool has raised £2m to expand its commercial work developing bacteria strains and adapt its tool for use with human and animal cells. Forge Genetics, a spin-out from the University of Nottingham, has secured funding from the Midlands Engine Investment Fund II, through its appointed fund [...]
Amorphical, developer of nano-amorphous mineral-based pharmacologic agents for health conditions, has announced positive interim results from its ongoing open-label clinical trial evaluating its investigational therapy for the treatment of moderate-to-severe Crohn’s disease. The data suggests that the investigational therapy, when added to best available therapy, supports meaningful clinical improvement and remission. The drug has been [...]
Biomedical engineers at Duke University have developed a platform that combines automated lab methods with artificial intelligence to design nanoparticles for drug delivery. The system helps researchers identify and optimise recipes for nanoparticles – tiny carriers that encapsulate drugs and deliver them to specific sites in the body. In a proof of concept, it created [...]
By Reddie & Grose It is impossible to escape the headlines on GLP-1 agonists such as Ozempic and Wegovy. Therefore, it seems reasonable to assume that the innovator behind these blockbuster drugs has robust, fail-safe strategies to protect their intellectual property worldwide. However, inaction by Danish company Novo Nordisk, who manufactures Ozempic and Wegovy, has [...]
Biostate AI, a company accelerating biological research through AI models, today announced the launch of K-Dense Beta, a comprehensive multi-agent AI research system that can compress research cycles from years to days, while eliminating hallucinations that plague generative AI models. In testing, K-Dense made a scientific breakthrough in longevity research, which will be published in [...]
The US FDA has approved clinical trials for genetically modified pig kidney transplants, moving the field from one-off cases into larger patient studies. Biotech firm eGenesis said on Monday it had received FDA clearance to begin human trials using kidneys from its gene-edited pigs. The company plans to transplant 33 patients over two and a [...]
Eli Lilly has launched a platform giving biotech firms access to AI models trained on proprietary data the company says cost more than US$1bn to build. Lilly TuneLab will provide smaller biotechnology companies with drug discovery models developed using years of the company’s research data. These include drug disposition, safety and preclinical datasets representing experimental [...]
Novo Nordisk, maker of Wegovy and Ozempic, will cut 11 per cent of staff after issuing a profit warning amid strong competition from US rival Eli Lilly. The Danish drugmaker’s decision affects 9,000 of its 78,400 employees, with 5,000 cuts in Denmark, as sales of Wegovy have slowed and cheaper generic versions have entered the [...]
A Q&A with Sebastien Coppe, CEO of One2Treat, on One2Treat Voice What motivated the development of the One2Treat Voice app, and how does it build upon One2Treat’s broader platform goals? The One2Treat Voice app was developed to address a central challenge in clinical development: ensuring that the primary endpoint, or primary analysis, of a clinical [...]
The Medical Research Council has awarded £1.45m to develop new efflux-resistant antifungal drugs for Candida auris and other Candida species, pathogens with mortality rates over 50 per cent. The grant will support research into invasive candidiasis, tackling rising drug resistance in fungi the World Health Organization (WHO) has classified as “critical”. Professor Miraz Rahman at [...]
