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AI system securely detects cancer from patient data

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Swarm learning can be used to help computers predict cancer without releasing the patient data from hospitals

A new way of using artificial intelligence to predict cancer from patient data without putting personal information at risk has been developed.

Artificial intelligence (AI) can analyse large amounts of data, such as images or trial results, and can identify patterns often undetectable by humans, making it highly valuable in speeding up disease detection, diagnosis and treatment.

But using the technology in medical settings can be controversial because of the risk of accidental data release.

Many systems are owned and controlled by private companies, giving them access to confidential patient data – and the responsibility for protecting it.

A team of researchers has set out to discover whether a form of AI called swarm learning could be used to help computers predict cancer in medical images of patient tissue samples, without releasing the data from hospitals.

Their research, titled ‘Swarm learning for decentralized artificial intelligence in cancer histopathology‘, was published on April 25 in Nature Magazine.

Swarm learning

Swarm learning trains AI algorithms to detect patterns in data that is held by a hospital or university, such as genetic changes within images of human tissue.

The swarm learning system then sends this newly trained algorithm – but importantly no local data or patient information – to a central computer.

There, it is combined with algorithms generated by other hospitals in an identical way to create an optimised algorithm.

This is then sent back to the original hospital, where it is reapplied to the original data, improving detection of genetic changes thanks to its more sensitive detection capabilities.

By undertaking this several times, the algorithm can be improved and one created that works on all the data sets.

This means that the technique can be applied without the need for any data to be released to third party companies or to be sent between hospitals or across international borders.

Researcher Phil Quirke, Professor of Pathology at Leeds, said: “We have shown that swarm learning can be used in medicine to train independent AI algorithms for any image analysis task.

“This means it is possible to overcome the need for data transfer without institutions having to relinquish secure control of their data.

“Creating an AI system which can perform this task improves our ability to apply AI in the future.”

Predicting cancer

The research was led by Jakob Nikolas Kather, Visiting Associate Professor at Leeds’ School of Medicine and Researcher at the University Hospital RWTH Aachen.

It included Professors Heike Grabsch and Phil Quirke, and Dr Nick West from Leeds’ School of Medicine.

The team trained AI algorithms on study data from three groups of patients from Northern Ireland, Germany and the USA.

They were tested on two large sets of data images generated at Leeds and were found to have successfully learned how to predict the presence of different subtypes of cancer in the images.

“Based on data from over 5,000 patients, we were able to show that AI models trained with swarm learning can predict clinically relevant genetic changes directly from images of tissue from colon tumours,” Dr Kather said.

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2 Comments

  1. Pingback: How pharma firms can get more value from unstructured data

  2. Pingback: PatientSource ophthalmology solution revolutionises care at Israel hospital

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